Stiaan van Zyl, national player of the Cobras, is nursing a thigh strain. He won’t make the trip to Pietermaritzburg for the four-day match against the Dolphins, starting on Thursday.
He will be replaced by Kleinveldt.
Kleinveldt managed 669 runs in the Sunfoil 3-Day Cup at an average of 44.60, with a century and six half-centuries in the 2014/2015-campaign while opening the innings for Western Province.
The 25-year old Njoloza finished with a match-haul of eight for 92 in powering Western Province to a seven-wicket win against KwaZulu Natal-Inland in their final league match.
If the fast bowler can repeat that performance, he might just set up a Cobras-win.
The Cobras have rung the changes for their final four-day match of the season. George F Linde gets another call-up as left-arm spinner, while Robin Peterson is rested.
The national off-spinner Dane Piedt is also part of the squad.
Piedt suffered a serious shoulder injury in September that needed surgery in October. He has not made a return to top-form yet.
It will be an important clash for Paterson on his old stomping ground. He will be keen to add to his 35 wickets in order to stay ahead of the rest of the chasing pack.
Rowan Richards of The Unlimited Titans is hot on his heels, having taken 34 wickets with three five-wicket hauls.
Paterson has been a revelation this season with his lion-hearted efforts.
The Cobras will require their senior stalwarts like Andrew Puttick, Dane Vilas, Justin Kemp and the skipper, Ontong, to produce excellent batting performances in support of the new star, Omphile Ramela.
Ramela would be keen to retain his momentum following his momentous batting performances against the Chevrolet Warriors and the Titans.
The Cobras squad for the Dolphins clash is: Justin Ontong (capt), Beuran Hendricks, Justin Kemp, Matthew Kleinveldt , George F Linde, Mpilo Njoloza, Dane Paterson, Dane Piedt, Andrew Puttick, Omphile Ramela, Mthokozisi Shezi, Dane Vilas